Products Technologies Imaging Mass Cytometry

Imaging Mass Cytometry

Gain unprecedented insights from highly multiplexed single-cell spatial biology

Imaging Mass Cytometry™ (IMC™) is a vital tool that allows researchers to gain an appreciation of the role of heterogeneity in cell function and assess complex phenotypes and tumor-immune interactions in the tissue and tumor microenvironment. Gain a deeper understanding of the spatial environment to answer important translational and clinical research questions in the context of disease.

When speed matters, get faster answers for cohort analysis and clinical studies with the second-generation Hyperion+™ Imaging System.

 

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Workflow

1

Design

Design panels using pathologist-verified Maxpar® antibodies conjugated to metal tags.

2

Stain

Stain tissues (FFPE or frozen) using familiar IHC protocols.

3

Image

Image up to 40 protein markers at single-cell resolution using the Hyperion™ Imaging System.

4

Analyze

Analyze images in minutes using the MCD™ Viewer and easily export for secondary analysis.

Using the Hyperion Imaging System, you can visualize the complex spatial biology of the tissue microenvironment with Imaging Mass Cytometry.

 

  • Single-cell resolution: allows accurate and quantifiable phenotyping and cell function assessment

  • No autofluorescence: reliable results when working with highly autofluorescent tissues like lung, gut, brain and skin

  • No time-consuming cyclic protocols: high-plex protein detection from formalin-fixed, paraffin-embedded or frozen tissue sections

  • Proven: hundreds of hands-on users and more than 130 peer-review published references

Expert insight on the transformation of precision medicine

Olivier Elemento, PhD
Professor, Physiology and Biophysics, Weill Cornell Medicine
Director, Englander Institute for Precision Medicine

Olivier Elemento shares his expert insight on the transformation of precision medicine. In this short video, Elemento describes why artificial intelligence, high-throughput sequencing and Imaging Mass Cytometry are becoming increasingly critical tools for personalizing treatments and improving patient outcomes.


Publications

Keep current with how Imaging Mass Cytometry (IMC) is used to gain deep spatial insights – see articles, news, bibliographies, tips and more. Check out the IMC Trending Topics and Publications.

IMC TRENDING TOPICS & PUBLICATIONS

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JOIN US

Join the hundreds of researchers globally who are using Imaging Mass Cytometry to phenotype the tissue microenvironment, stratify samples and discover biomarkers to gain therapeutic insights that address significant translational and clinical research questions.

See more than 130 publications

Events

Join us for one of our upcoming events or watch on demand.

VIEW IMC EVENTS

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Mar 28 - Mar 30

Location

Forum Labo in Paris, France

Mar 28 - Mar 30

Location

EACR/OECI (European Association for Cancer Research/Organisation of European Cancer Institutes) Molecular Pathology Approach to Cancer in Bergamo, Italy

Mar 28 - Mar 29

Location

Immuno UK in London, UK

Mar 28

Virtual

Scientist in the Spotlight | Toward identifying immune dysfunction signatures in myelodysplastic neoplasms

Apr 04 - Apr 05

Location

SIG (The Genetics Society) Seed Plant Research Meeting 2023 in Durham, England

Apr 14 - Apr 19

Location

AACR (American Association for Cancer Research) in Orlando, FL

Apr 16 - Apr 18

Location

CIB (CROP Innovation & Business) in Amsterdam, Netherlands

Apr 19 - Apr 21

Location

SIC 2023 | XVII Congress of the Iberian Society of Cytometry in Madrid, Spain

Apr 20 - Apr 22

Location

35th Tumor Genetic Workshop 2023 in Rostock, Germany

Apr 20 - Apr 23

Location

DGfI TIMO XVI (German Society for Immunology) in Halle, Germany

Unless explicitly and expressly stated otherwise, all products are provided for Research Use Only, not for use in diagnostic procedures. Find more information here.