Immune Profiling
Maxpar Direct Immune Profiling Assay and Maxpar Pathsetter software
Introducing the first complete sample-to-answer solution for single-cell high-dimensional immune profiling of human PBMC and whole blood, the Maxpar® Direct™ Immune Profiling Assay™ and Maxpar Pathsetter™ software. Each provides the data quality and reproducibility required to capture the highly individual nature of immune response in health and disease.
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We can help you convert your fluorescence panel and find a service provider.
The technical details: populations, clones and workflows
Designed as a simple single-tube workflow, the system brings together CyTOF® technology on the CyTOF XT™ and Helios™ mass cytometry systems, a dry-format 30-marker antibody panel and automated Maxpar Pathsetter software, enabling identification of 37 immune cell populations.
Get more details from the Maxpar Direct Immune Profiling flyer.
Single-tube antibody panel design. All antibody clones used in the kit are familiar and industry-proven.
The 37 immune cell subsets identified using the Maxpar Direct Immune Profiling Assay and Maxpar Pathsetter software.
Samples stained with the Maxpar Direct Immune Profiling Assay can be fixed, frozen and stored for analysis at a later time or at another location.
Broad adoption by consortia and in clinical research studies
The Maxpar Direct Immune Profiling System has been adopted for use by multiple consortia and in clinical research studies based on its ease of use and reproducibility lot-to-lot, run-to-run and site-to-site. Learn more below about how this comprehensive and reliable approach to immune monitoring is reducing time to results and lowering cost for large studies.
Bibliography: Maxpar Direct Immune Profiling System
Proven performance and reproducibility
The reproducibility of the Maxpar Direct Immune Profiling System has been demonstrated run-to-run and site-to-site.1,2
- Rouphael, N. et al. “Immunophenotyping assessment in a COVID-19 cohort (IMPACC): A prospective longitudinal study.” Science Immunology 6 (2021): eabf3732.
- Bagwell, C.B. et al. “Multi-site reproducibility of a human immunophenotyping assay in whole blood and peripheral blood mononuclear cells preparations using CyTOF® technology coupled with Maxpar® Pathsetter™, an automated data analysis system.” Cytometry Part B Clinical Cytometry 98 (2020): 146–160.
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The Maxpar Direct Assay: An expandable 30-marker dry-format cytometric assay for deep immune profiling. |
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See the benefits of CyTOF XT for immune profiling. |
CUSTOMIZATION LETS YOU GO EVEN DEEPER
The Maxpar Direct Immune Profiling Assay was designed with customization in mind.
Choose from 8 ready-to-go 40-plus-marker panel options. Profile T, B, NK and myeloid cells for activation status and cytokine production, all in a single tube.
Building a 47-marker flow cytometry panel to explore antigen-specific immune responses.
Webinars
Reimagine Flow Cytometry
Customization of the Maxpar Direct Immune Profiling Assay and Maxpar Pathsetter for Use in a Biotech Setting
Molecular Characterization of CAR T Cells Using Mass Cytometry
Bringing Immune Profiling One Step Closer to Clinics with Cytometry by Time-of-Flight (CyTOF)
Sasidhar Vemula, PhD
Lead Scientist
Translational Biomarker Solutions
Labcorp Drug Development
Vanderbilt University
Watch now
CyTOF in the Cancer Immune Monitoring and Analysis Centers (CIMAC): Standardization and Harmonization
Holden Maecker, PhD
Professor of Microbiology and Immunology
Director of the Human Immune Monitoring Center Stanford University
A Complete Immune Monitoring Solution with CyTOF: Ideal for Pandemics and Beyond
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Customer Stories
Learn more about how our customers are leveraging the Maxpar Direct Immune Profiling Assay.
VIEW ALLLori Turner, PhD
A quick pivot to COVID-19 research with CyTOF
Benjamin Terrier, MD, PhD
Discovering a hallmark phenotype of COVID-19
Resources
Publications
User guides
Technical documents
Don’t have a CyTOF system? We can help!
Maxpar Direct Assays are still the best option for your study if you want convenience, flexibility and consistency.
Maxpar reagents are so robust you can stain, freeze, store and ship your samples for analysis to a CyTOF service provider.
Unless explicitly and expressly stated otherwise, all products are provided for Research Use Only, not for use in diagnostic procedures. Find more information here.