» Accelerate your research with new standardized Mouse Immuno-Oncology IMC Panel Kits
Introducing the ready-to-go 28-plex Maxpar® OnDemand™ Mouse Immuno-Oncology IMC™ Panel Kit, made up of 4 modules that can be used together or separately to allow for optimal study design.
» Ready-to-go mouse and human standardized panel kits
Mouse and human IMC panel kits enable translational researchers to overcome obstacles to therapeutic efficacy through the ability to evaluate post-treatment response quantitatively and spatially in the tumor microenvironment (TME).
The Maxpar Human Immuno-Oncology IMC Panel Kit is made up of three panels, and the Maxpar OnDemand Mouse Immuno-Oncology IMC Panel Kit is made up of four panels.
Maxpar OnDemand Mouse Immuno-Oncology IMC Panel Kits
Mouse models are widely used for translational research. To provide researchers with a deep understanding of the TME, these mouse panel kits will help assess immunological and oncological processes that dictate tumor growth, metastasis and immune response across multiple mouse tissues:
- Maxpar OnDemand Mouse Tissue Architecture IMC Panel Kit (7-plex, Cat. No. 9100001)
- Maxpar OnDemand Mouse Cancer Cell Process IMC Panel Kit (10-plex, Cat. No. 9100002)
- Maxpar OnDemand Mouse Immune Phenotyping IMC Panel Kit (8-plex, Cat. No. 9100003)
- Maxpar OnDemand Mouse Immune Activation IMC Panel Kit (3-plex, Cat. No. 9100004)
- A fifth panel, the Maxpar OnDemand Mouse Immuno-Oncology IMC Panel Kit (28-plex, Cat. No. 9100005), combines the above four panels. Each kit contains pre-sourced, curated, metal-tagged and ready-to-go Maxpar or Maxpar OnDemand Antibodies.
Maxpar Human Immuno-Oncology IMC Panel Kits
To provide researchers with a rich, insightful understanding of tumor-infiltrating lymphocyte activation and infiltration, T cell activation and tissue architecture across several human cancer types, three multiplex human IO panel kits are available:
- Maxpar Human Tumor-Infiltrating Lymphocytes IMC Panel Kit (9-plex, Cat. No. 201506)
- Maxpar Human Immune Activation IMC Panel Kit (5-plex, Cat. No. 201503)
- Maxpar Human Tissue Architecture IMC Panel Kit (6-plex, Cat. No. 201507)
- A fourth panel, the Maxpar Human Immuno-Oncology IMC Panel Kit (18-plex, 201508), combines the above three IO panels. Each kit contains pre-sourced, pre-tagged, pathologist-verified antibodies and a nucleic acid stain.
» Flexible options to customize your panel.
Customize your panel by mixing and matching panel kits or by adding your choice of individual Maxpar or Maxpar OnDemand Antibodies in other available channels for Imaging Mass Cytometry. Or consider custom conjugation as an option to easily add to your panel. Standardize and jump-start panel development and save significant time and cost using these pre-selected immuno-oncology (IO) panel kits.
» Segment With Confidence Using the IMC Cell Segmentation Kit
Get accurate and reliable cell segmentation using the IMC Cell Segmentation Kit to facilitate an end-to-end workflow for single-cell data analytics.
» Easily build or expand your panel from a selection of over 300 human and mouse antibodies.
The Maxpar and Maxpar OnDemand catalog portfolio of antibodies offers metal-conjugated antibodies for formalin-fixed, paraffin-embedded (FFPE) and frozen tissues. Both Maxpar and Maxpar OnDemand are high-quality antibodies that do not exhibit autofluorescence and can be used to characterize a wide range of tissues. The high purity and choice of metal isotopes ensure minimal background noise from signal overlap or endogenous cellular components.
The complete list references 242 antibodies, with over 300 available based on additional metal options for some of our more popular antibodies through Maxpar OnDemand as included in the lists below. If other species reactivity is important to you, once at the list, to the left you can easily choose other species reactivity, as reported by the antibody vendor.
» Maxpar Antibodies for FFPE and frozen tissue
The Maxpar catalog features more than 200 metal-labeled antibodies with a focus on immune and oncology targets. Design your own custom panel to analyze immunity, cancer progression or cancer immunotherapy research targets.
Maxpar antibodies for frozen tissue support rapid and easier panel development with fewer steps since antigens are in their native state and epitope retrieval is not required.
» Questions about staining?
Check out the IMC Trending Topics Toolbox section on optimizing your staining for links to protocols and other resource.
Human and mouse antibodies in the Maxpar catalog
Human pathologist-verified antibodies for IMC for FFPE and frozen tissues. The technical note Imaging Mass Cytometry Antibody Verification Process describes this verification process. All of our Maxpar human FFPE or frozen antibodies fall in this category.
Other human antibodies are available as part of our Maxpar OnDemand offering.
» Maxpar OnDemand IMC Antibodies expand panel-building options
Maxpar OnDemand Antibodies provide a flexible option, making panel design easier. The doubling of our antibody portfolio with Maxpar OnDemand Antibodies for Imaging Mass Cytometry (IMC) was announced at our October 2021 event IMC Summit: Uncovering Spatial Biology. Hear about this exciting antibody collection from Product Manager Clinton Hupple.
Maxpar OnDemand Antibodies are ordered in the same way as any of our catalog products. They come in fixed 15 µg (0.5 mg/mL) vials and ship within six business days.
» How we ensure quality
Because Maxpar OnDemand Antibodies are made in small batches, there are differences in the QC process compared with our traditional Maxpar catalog antibodies, which are made in large lots. Each Maxpar OnDemand Antibody clone is pre-verified by IMC in a biologically relevant tissue. Each batch then undergoes a biochemical verification to confirm performance. This streamlined process balances consistency, flexibility and fast turnaround time.
For a list of currently available Maxpar OnDemand Antibodies, download the TDS.
» Segment With Confidence Using the IMC Cell Segmentation Kit
Learn more about how to get accurate and reliable cell segmentation using the IMC Cell Segmentation Kit to facilitate an end-to-end workflow for single-cell data analytics. For more guidance and resources, check out the IMC Trending Topics Toolbox section on Performing Cell Segmentation.
Custom Antibody Conjugation
When your study calls for new antibodies or specific antibody configurations, consult our team of experts for Custom Conjugation Services to tailor your antibody panels for collecting high-impact data. Our Custom Conjugation Services speed you from design to discovery with made-to-order metal labeling for antibodies not currently listed in the Maxpar catalog, or alternative metal tagging for all listed items. Choose from 37 nonoverlapping pure metal tags.
Segment with confidence using the IMC Cell Segmentation Kit. Benefit from a robust end-to-end workflow for single-cell data analytics for your high-plex IMC data. The IMC Cell Segmentation Kit includes three individual plasma membrane markers for improved nucleus and plasma membrane demarcation.
Labeling kits and buffer
Maxpar Labeling Kits
With Maxpar metal-labeling kits you can tag IgG clones with your choice of up to 35 metals. Order them individually or as sets, with each kit containing enough material to conjugate 4 antibodies in 100 μg amounts.
Multimetal Labeling Kit
The multimetal Maxpar kit contains a total of 40 reactions for conjugating metals to monoclonal antibodies, with up to 10 different metals of your choice (each at 4 reactions).
Maxpar Water provides optimal and consistent staining conditions.