Area of Interest Neuroscience Neuroscience with Imaging Mass Cytometry


See neural tissues clearly

The high heterogeneity and autofluorescence of brain and neural tissue present technical challenges when using conventional imaging techniques to decipher different cell types and intricate spatial relationships in the study of neurodegenerative disease or neuro-oncology.

Imaging Mass Cytometry™ (IMC™) produces clear, easy-to-interpret signals from neural tissue, eliminating autofluorescence interference with metal-labeled antibodies.

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Application of neuro-oncology IMC panel on human and mouse tumors of mixed or non-glial origin. 

Application of neuro-oncology IMC panel on human and mouse tumors of mixed or non-glial origin 

Mapping the neuro-oncological cellular landscape

Spatial phenotyping with IMC enables comprehensive assessment of the structural and cellular organization of the tumor microenvironment in neural tissues, including activation of immuno-oncological processes.

See the neuro-oncology poster

See the neuro-oncology poster summary

Neuro-oncology panel kits for Imaging Mass Cytometry

Identify neural cell lineages and immune cell infiltration in spatial context to better understand disease progression.

Try one of our ready-made panels or bundles or explore our comprehensive catalog of immune markers. Our easy panel design process makes integrating new markers simple.

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Learn about the power of the high-plex Maxpar OnDemand Mouse Neuro-Oncology IMC Bundle to enable single-cell analysis for fast and accurate brain tumor and immune cell phenotyping.

Read the application note

Maxpar OnDemand Mouse Neuro-Oncology IMC Bundle

Study neurodegeneration spatial complexity in context

Pathological proteins have emerged as a common mechanism for the progression of various neurodegenerative diseases. Discover the spatial distribution of these key proteins in neural tissues using pre-designed IMC panels for the study of neurodegenerative diseases in formalin-fixed, paraffin-embedded (FFPE) tissue sections.


View Application note


Get critical insights into common neurodegenerative proteinopathies or mixed pathologies as seen in synucleinopathy and tauopathy neurodegenerative conditions.

Add compatible panels for deeper insights

Capture a more complete view of neurodegeneration by combining any neurodegeneration panel with human immuno-oncology IMC subpanels, the Maxpar Neuro Phenotyping IMC Panel Kit, the Maxpar IMC Cell Segmentation Kit and Cell-ID™ Intercalator. 

View the application note to see how three different high parameter 41-marker panels for neurodegenerative disease can be easily assembled, with a particular focus on insights from Alzheimer’s disease tissue.

View Application note


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Daniela Quail, PhD

Webinar: Spatial Dissection Of Tumor Immune Microenvironment

Daniela Quail, PhD
Assistant Professor, Rosalind and Morris Goodman Cancer Institute and Department of Physiology, McGill University

Quail describes the use of Imaging Mass Cytometry to understand immune dynamics in tumors – first in the brain tumor microenvironment to identify new cell populations that might help understand tumor biology and second in non-small-cell lung cancer patients to predict recurrence and survival outcomes.

Unless explicitly and expressly stated otherwise, all products are provided for Research Use Only, not for use in diagnostic procedures. Find more information here.