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Join us at IMMUNOLOGY2025™ | Booth 334

Setting the standard for immune insights

Our high-content solutions in serum, spatial and single-cell proteomics
and multi-omics offer the highest levels of content, precision andunique scalability in the life science industry.

Exclusive Speaker Session

Multi-Omic Breakthroughs in Clinical Trials: Immune Monitoring for Precision Disease Detection

Monday, May 5  |  8:30 - 9:15 AM
Exhibitor Workshop Room 1 - Kamehameha

With the growing adoption of multi-omic technologies in​ clinical studies, integrating multivariate findings can​ enhance predictive insights into immunotherapy​response. Helen McGuire, PhD, from the University of​ Sydney, will present a simplified workflow for immune​ monitoring in multi-site clinical trials and an innovative​ approach to integrating multi-omic datasets to improve​ outcome predictability. She will describe a novel​ proteomic immune signature of lung cancer​ non-responsiveness that can predict failure to respond​ to checkpoint therapies, offering a powerful tool for​ treatment decisions.​

Helen McGuire, PhD

Helen McGuire, PhD
University of Sydney

Helen McGuire, PhD Biography

Dr. Helen McGuire earned her PhD from the Garvan Institute of Medical Research in Sydney in 2011. She was awarded an NHMRC postdoctoral fellowship to train at Stanford University under Professor Mark Davis at the Institute for Immunity, Transplantation and Infection, a leader in single-cell proteomics and CyTOF technology. After returning to Australia, she joined Professor Barbara Fazekas at the Ramaciotti Facility for Human Systems Biology, University of Sydney, where she helped introduce mass cytometry to Australian medical research.

Reserve your spot at our speaker session

See our poster sessions

Sunday, May 4 – Tuesday, May 6

Sunday, May 4

  • Application of comprehensive multi-omic immune profiling strategy achieves superior checkpoint immunotherapy response prediction in lung cancer

Monday, May 5

  • 9:00am Room 312 (oral presentation)

    Novel functional diversity of human T cells is revealed as a result of the unprecedented resolution of intracellular cytokines transcription factors and phosphoproteins using Mass Cytometry (CyTOF)
  • Accelerating immuno-oncology research with flexible workflows using modular Flex-Fit CyTOF panels
  • High-plex spatial analysis of T cell exhaustion using Imaging Mass Cytometry for immuno-oncology studies
  • Flexible and comprehensive phenotyping of tumor and peripheral blood mononuclear cells in endometrial carcinoma.

Tuesday, May 6

  • Measurement of Human Immune Cells Producing the Immunosuppressive/Cell Repair Cytokines TGF-b IL-10 and Others Achieved Using a Novel 50-Parameter CyTOFIntracellular Cytokine Staining
  • A Comprehensive Immune Monitoring Strategy for Multicenter Clinical Trials to Achieve High-Quality Immunophenotyping of Individuals From Remote Communities in Australia
  • Detecting clinically relevant low-abundance tissue biomarkers using Imaging Mass Cytometry
  • Characterization of cellular diversity and immune landscape in Mouse Glioblastoma using whole slide imaging modes of high-plex Imaging Mass Cytometry
  • Using proteomic surrogates to improve understanding of cardiometabolic risks in IMIDs

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