b'Fast screening of the entire slide combined with single-cell analysisView the Applying three rapid imaging modes to a tissue microarray (TMA) containing dozens of humanstudy detailsglioma cores identified the spatial distribution of over 40 distinct molecular markers.Preview Mode Cell ModePreview Mode was applied to rapidly screen tumor cores for expression signatures associated with tumor immuno-oncology processes. This enabled biomarker-guided selection of areas in tumor tissue that were imaged at higher resolution and analyzed with single-cell analysis using Cell Mode.Tissue Mode facilitates identification of prominent features in all TMA coresTissue ModeFrom larger samples to TMA cores, Tissue Mode generates a high-quality scan of the entire tissue section in a matter of hours with higher spot-size ablations enabling entire tissue analysis using pixel-clustering methods. This is an especially high-throughput modality with TMAs, as 18 2 mm TMA cores can be imaged in 1 hour and 35 minutes. In the figure above, Tissue Mode visualizes tissue compartments and indicates high heterogeneity of human glioma cores. Cores of interest are selected for subsequent pixel-clustering analysis.18 2 mm TMA cores can be imagedin 1 hour and 35 minutes'