Imaging Mass Cytometry
Gain unprecedented insights from highly multiplexed single-cell spatial biology
Imaging Mass Cytometry™ (IMC™) is a vital tool that allows researchers to gain an appreciation of the role of heterogeneity in cell function and assess complex phenotypes and tumor-immune interactions in the tissue and tumor microenvironment. Gain a deeper understanding of the spatial environment to answer important translational and clinical research questions in the context of disease.
When speed matters, get faster answers for cohort analysis and clinical studies with the second-generation Hyperion+™ Imaging System.
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Workflow
1
Design
Design panels using pathologist-verified Maxpar® antibodies conjugated to metal tags.
2
Stain
Stain tissues (FFPE or frozen) using familiar IHC protocols.
3
Image
Image up to 40 protein markers at single-cell resolution using the Hyperion™ Imaging System.
4
Analyze
Analyze images in minutes using the MCD™ Viewer and easily export for secondary analysis.
Using the Hyperion Imaging System, you can visualize the complex spatial biology of the tissue microenvironment with Imaging Mass Cytometry.
- Single-cell resolution: allows accurate and quantifiable phenotyping and cell function assessment
- No autofluorescence: reliable results when working with highly autofluorescent tissues like lung, gut, brain and skin
- No time-consuming cyclic protocols: high-plex protein detection from formalin-fixed, paraffin-embedded or frozen tissue sections
- Proven: hundreds of hands-on users and more than 130 peer-review published references
Expert insight on the transformation of precision medicine
Olivier Elemento, PhD
Professor, Physiology and Biophysics, Weill Cornell Medicine
Director, Englander Institute for Precision Medicine
Olivier Elemento shares his expert insight on the transformation of precision medicine. In this short video, Elemento describes why artificial intelligence, high-throughput sequencing and Imaging Mass Cytometry are becoming increasingly critical tools for personalizing treatments and improving patient outcomes.
Publications
Keep current with how Imaging Mass Cytometry (IMC) is used to gain deep spatial insights – see articles, news, bibliographies, tips and more. Check out the IMC Trending Topics and Publications.
IMC TRENDING TOPICS & PUBLICATIONS
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Applications
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Join the hundreds of researchers globally who are using Imaging Mass Cytometry to phenotype the tissue microenvironment, stratify samples and discover biomarkers to gain therapeutic insights that address significant translational and clinical research questions.
See more than 130 publications
Feb 23 - Feb 26
Location
Aquaculture America in New Orleans, LA
Mar 05 - Mar 10
Location
DGfI Spring School on Immunology in Ettal, Bavaria
Mar 07 - Mar 09
Location
GPZ/GPW (Working Group Seed Science and Certification) & VDLUFA (Section IV Seeds) Seed Symposium 2023 in Nossen, Germany
Mar 09 - Mar 11
Location
Congress of the Association of Morphologists and the College of Histologists, Embryologists and Cytogeneticists in Lille, France
Mar 09 - Mar 10
Location
7th Annual Markets and Markets Next-Gen Immuno-Oncology Conference in London, UK
Mar 13 - Mar 15
Location
UNIGE (Conference of the International PhD Program in Life Sciences of The University of Geneva) in Geneva, Switzerland
Mar 13 - Mar 15
Location
XXI Scientific Convention in Riva del Garda, Italy
Mar 16 - Mar 17
Location
Brest Mass Days in Brest, France
Mar 20 - Mar 23
Location
10th Gene Quantification Event qPCR, dPCR and NGS in Freising-Weihenstephan, Germany
Mar 28 - Mar 30
Location
Forum Labo in Paris, France
Resources
Flyers & brochures
Spotlight articles
Application notes
Technical documents
FAQs
Protocols
Unless explicitly and expressly stated otherwise, all products are provided for Research Use Only, not for use in diagnostic procedures. Find more information here.