Products & Services Technologies Imaging Mass Cytometry

Imaging Mass Cytometry

Gain unprecedented insights from highly multiplexed single-cell spatial biology

Imaging Mass Cytometry™ (IMC™) is a vital tool that allows researchers to gain an appreciation of the role of heterogeneity in cell function and assess complex phenotypes and tumor-immune interactions in the tissue and tumor microenvironment. Gain a deeper understanding of the spatial environment to answer important translational and clinical research questions in the context of disease.

When speed matters, get faster answers for cohort analysis and clinical studies with the second-generation Hyperion+™ Imaging System.

 

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Workflow

1

Design

Design panels using pathologist-verified Maxpar® antibodies conjugated to metal tags.

2

Stain

Stain tissues (FFPE or frozen) using familiar IHC protocols.

3

Image

Image up to 40 protein markers at single-cell resolution using the Hyperion™ Imaging System.

4

Analyze

Analyze images in minutes using the MCD™ Viewer and easily export for secondary analysis.

Using the Hyperion Imaging System, you can visualize the complex spatial biology of the tissue microenvironment with Imaging Mass Cytometry.

 

  • Single-cell resolution: allows accurate and quantifiable phenotyping and cell function assessment

  • No autofluorescence: reliable results when working with highly autofluorescent tissues like lung, gut, brain and skin

  • No time-consuming cyclic protocols: high-plex protein detection from formalin-fixed, paraffin-embedded or frozen tissue sections

  • Proven: hundreds of hands-on users and more than 130 peer-review published references

Expert insight on the transformation of precision medicine

Olivier Elemento, PhD
Professor, Physiology and Biophysics, Weill Cornell Medicine
Director, Englander Institute for Precision Medicine

Olivier Elemento shares his expert insight on the transformation of precision medicine. In this short video, Elemento describes why artificial intelligence, high-throughput sequencing and Imaging Mass Cytometry are becoming increasingly critical tools for personalizing treatments and improving patient outcomes.


Publications

Keep current with how Imaging Mass Cytometry (IMC) is used to gain deep spatial insights – see articles, news, bibliographies, tips and more. Check out the IMC Trending Topics and Publications.

IMC TRENDING TOPICS & PUBLICATIONS

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JOIN US

Join the hundreds of researchers globally who are using Imaging Mass Cytometry to phenotype the tissue microenvironment, stratify samples and discover biomarkers to gain therapeutic insights that address significant translational and clinical research questions.

See more than 130 publications

Events

Join us for one of our upcoming events or watch on demand.

VIEW IMC EVENTS

VIEW ALL EVENTS

Dec 05 - Dec 08

Location

BSI (British Society for Immunology) Congress in Liverpool, England

Dec 07 - Dec 08

Location

Digital Pathology & AI Congress in London, England

Dec 08

Virtual

IMC Forum: Considerations for High-Plex Imaging Data Analysis Session II

Dec 14

Webinar

Scientist in the Spotlight - Samarth Mathur, Ecology and Organismal Biology Department at Ohio State University

Jan 05 - Jan 06

Physical-and-Virtual

Flow Cytometry Facilities Meeting 2023 in London, UK

Jan 13 - Jan 18

Location

PAG 30 (Plant and Animal Genome Conference) in San Diego, CA

Jan 19 - Jan 20

Location

DRFZ (German Rheumatism Research Centre) 6th German Mass Cytometry User Forum in Berlin, Germany

Feb 01 - Feb 03

Location

3rd Swiss Cytometry Meeting in Zürich, Switzerland

Mar 05 - Mar 10

Location

DGfI Spring School on Immunology in Ettal, Bavaria

Mar 07 - Mar 09

Location

GPZ/GPW (Working Group Seed Science and Certification) & VDLUFA (Section IV Seeds) Seed Symposium 2023 in Nossen, Germany

Unless explicitly and expressly stated otherwise, all products are provided for Research Use Only, not for use in diagnostic procedures. Find more information here.