How can we look at so many cells at once?
To understand brain function, it is essential to know not only what cells are present, but also what they do. And while the brain is incredibly complex, an in-depth understanding of the purpose of each cell and how they interact can direct how we prevent, address and cure dysfunctions caused by disease and degeneration.
Influences of neurological disease
Neurodegeneration
Immune response plays a significant role in the progression of neurodegenerative diseases such as Parkinson’s disease, Alzheimer’s disease and multiple sclerosis. The ability to simultaneously explore numerous biological outputs that provide new perspectives on the extensive composition of the neurodegenerative brain can open avenues for potential new diagnostic and therapeutic applications.
Cancer
Gliomas present a complex form of brain cancer that is challenging to diagnose and treat, with a median survival of just over one year after diagnosis for primary glioblastoma (GBM). GBM can occur as multi-lesion, remote or diffuse tumors, and often contains a tumor microenvironment that is devoid of peripheral immune cells.
Inflammation
Brain inflammation can result in neuronal cell dysfunction and synaptic injury with short-term impairment that can increase the risk of neuronal cell death and long-term cognitive decline and dementia. Following the trajectory of acute and chronic neuroinflammation can help determine affected cell subsets and associated proteins.
In the spotlight
Browse through the Image Lookbook to explore a detailed view of the cellular and structural composition of neural tissues – unlocking new understanding of neuro-oncology and neurodegeneration.
Solutions at all levels of research
Standard BioTools’ uniquely scalable technologies offer the highest levels of content and precision in the life science industry, enabling researchers to discover novel biological insights not accessible by other approaches.
Featured Article: Deciphering one of the most challenging forms of cancer
Take an in-depth look into the spatial landscape of neoplastic brain tissue
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