Standard BioTools

Here’s an example of fast screening of an entire tissue microarray containing dozens of human glioma cores using Imaging Mass Cytometry™, identifying the spatial distribution of over 40 distinct molecular markers. Preview Mode on Hyperion XTi™ was applied to rapidly screen for expression signatures associated with tumor #immunooncology processes. This enabled biomarker-guided selection of areas in tumor tissue that were imaged at higher resolution and analyzed with #singlecell analysis using Cell Mode. Get more details on this and other applications for high-plex tissue imaging: https://lnkd.in/gwSDzSaD #lookbook #tissueimaging #biomarkers

Hyperion™ XTi now offers three modes for rapid and detailed spatial biology analysis: (1) Preview Mode for quick whole slide overviews; (2) Tissue Mode for whole slide imaging in real time; and (3) Cell Mode to analyze regions of interest at single-cell resolution. By leveraging the different modes on Hyperion XTi™, researchers can quickly visualize tissue heterogeneity in minutes and can then conduct deeper analysis on targeted regions. Learn about flexible image acquisition and analysis: https://lnkd.in/g3pgxVuJ #labautomation #spatialbiology #highthroughput #dataquality

What is it about microfluidics anyway? Because of the smaller scale and computational aspect of the instrument that processes a microfluidic circuit, one system can be made to do multiple things, such as real-time PCR and NGS library preparation. This means no more cluttered benchtops and less time-consuming protocols. See more answers: https://lnkd.in/gHcmsSTd #labautomation #biomarkers #discovery #screening

Standard BioTools™ understands that each grant is unique and must be supported with relevant documentation and materials. We offer an array of documents for your research and instrumentation grant application. Take a look through our available resources, and if you need more help, just let us know! Want to accelerate your research? Explore our resources: https://lnkd.in/gpFHhNYg #grant #resources #globalsupport

Panel design for multiplexed tissue imaging can be challenging, so why not take a modular approach? Spend less time and easily optimize your experiment with our newest 31-plex Human Immuno-Oncology IMC™ Panel. The Human Immuno-Oncology IMC Panel is composed of a set of pre-configured subpanels with the option to easily add more markers or compatible expansion panels to explore your specific research questions. Looks at tissue architecture, cell interaction and single-cell phenotypic and functional markers at once. Here’s how: https://lnkd.in/g_NWvP28 #tissueimaging #proteins #multiplexedimaging #immunooncology

We are thrilled to be in Manchester for the British Society for Immunology Neuro-Immunology Symposium, discussing research on brain injury, regeneration, peripheral neuroimmune mechanisms, neurodegenerative disease and CNS infection. Today, Filomena Spada, PhD, will be giving a presentation on high-plex whole slide #spatialbiology assays powered by the Hyperion™ XTi Imaging System. Take 10 minutes to learn about comprehensive immune cell characterization and detailing cellular interactions in different neurological conditions. More on #Neuroimmuno24: https://lnkd.in/dF4xNn44 #neuroscience #CyTOF

Traditional methods for understanding patient response to immune checkpoint blockade therapy in triple-negative #breastcancer provide limited information, making it difficult to predict which patients will benefit most. But what if we could analyze the tumor microenvironment at a whole new level of detail? Join us for a webinar, hosted by Giampaolo Bianchini, MD, from the San Raffaele Hospital, who will talk about a recently published Nature paper that delves into the power of Imaging Mass Cytometry™ for precision immuno-oncology. Mark your calendar: https://lnkd.in/gvA2vJnp #immunotherapy #immunology #cancerresearch #precisionmedicine

When exhaustion sets in, pushing through to finish the job can be tough. This couldn’t be more true than for #Tcells working to destroy a tumor … T cell exhaustion is well documented in all kinds of diseases, and is an integral part of the cancer-fighting process that we are only beginning to fully understand – a process that immunotherapy, particularly immune checkpoint blockades, aims to help modulate. Read our latest #scienceblog highlighting a foundational study on T cell exhaustion as it applies to #breastcancer: https://lnkd.in/gT9ziTxq #CyTOF #imaging

Hello from Minneapolis! What a great start to #ABRF2024, with a well-attended talk from Alexander Scalia, Technical Support Scientist, exploring how the SomaScan® Assay enables high throughput, reproducible data and experimental control for large-scale projects, while fostering collaborative biomarker discovery initiatives. With over 11,000 protein data points measured simultaneously in a single sample, the SomaScan® platform provides unparalleled pathway coverage, pQTL insights and deeper discoveries, accelerating breakthroughs in complex biological systems. Stop by Booth 406 to learn about new technologies that can enhance any core facility! Assn of Biomolecular Resource Facilities (ABRF) #proteomics #biomarkers SomaLogic

You are invited to a CYTO® 2024 lunchtime Exhibitor Spotlight Theater with Jennifer Snyder-Cappione, PhD. She will present ‘Exceptional Resolution of Anti-Inflammatory Cytokines by Mass Cytometry’ – discussing how CyTOF® flow cytometry can enhance understanding of the dynamics of immune responses and open new avenues for targeted therapies. Come have lunch with us on Tuesday, May 7, at 12:15–1:15 pm and hear about her team's experimental approach and results from three head-to-head comparisons of small (12–13-plex) intracellular staining panels using a spectral flow cytometer and the CyTOF XT™ mass cytometer: https://lnkd.in/gXm-Qiiy #CYTO24 #CyTOF #inflammation